Removal of chlorpheniramine by nZVI/H2O2 was studied for the first time.
The optimal reaction conditions were determined for chlorpheniramine degradation.
Degradation pathway of chlorpheniramine in the nZVI/H2O2 system was proposed.
NDMA was formed during the decomposition of chlorpheniramine by nZVI/H2O2.
NDMA FP was significantly reduced by nZVI/H2O2 reaction.