Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway
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- 作者：Hong Yaoa ; 1 ; Changsheng Hub ; 1 ; Lianhong Yina ; Xufeng Taoa ; Lina Xua ; Yan Qia ; Xu Hana ; Youwei Xua ; Yanyan Zhaoa ; Changyuan Wanga ; Jinyong Penga ; jinyongpeng2008@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acute liver injury ; Dioscin ; Lipopolysaccharide ; Inflammation ; TLR4/MyD88 signal pathway
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：36
- 期：Complete
- 页码：132-141
- 全文大小：2493 K
文摘
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Dioscin protected LPS-induced liver injury in mice and rats.
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Dioscin protected LPS-induced liver injury in AML-12 and HepG-2 cells.
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Dioscin significantly attenuated inflammation in vivo and in vitro.
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Dioscin adjusted TLR4/MyD88 signal pathway.