Assessment of Pulp Regeneration Induced by Stem Cell Therapy by Magnetic Resonance Imaging
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- 作者：Koichiro Iohara ; DDS ; PhD&lowast ; ; Masanori Fujita ; DDS&lowast ; ; &dagger ; ; Yoshiko Ariji ; DDS ; PhD&Dagger ; ; Misato Yoshikawa ; PhD§ ; ; Hideto Watanabe ; MD ; PhD‖ ; Akihiko Takashima ; MD ; PhD§ ; ; Misako Nakashima ; DDS ; PhD&lowast ; ; misako@ncgg.go.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Efficacy ; MRI ; pulp regeneration
- 刊名：Journal of Endodontics
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：42
- 期：3
- 页码：397-401
- 全文大小：1161 K
文摘
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This study was designed to evaluate the usefulness of MRI for detecting tooth vitality after stem cell transplantation for pulp regeneration.
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The signal intensity (SI) of normal teeth was significantly higher than that of nonvital pulpectomized teeth and collagen transplanted nonregenerated teeth.
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Regenerated pulp tissue showed a high SI similar to normal teeth.
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The changes in SI of MRI in the regenerated pulp were consistent with histopathologic findings, showing a potential noninvasive method to serially access the effectiveness of pulp regeneration elicited by stem cell therapy.