A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in mice
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- 作者：Chrislean Jun Botanasa ; 1 ; Seong Shoon Yoonb ; 1 ; June Bryan de la Peñ ; aa ; Irene Joy dela Peñ ; aa ; Mikyung Kima ; Taeseon Wooa ; Joung-Wook Seob ; Choon-Gon Jangc ; Kyung-Tae Parkd ; Young Hun Leed ; Yong Sup Leed ; Hee Jin Kima ; msheejin@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jae Hoon Cheonga ; cheongjh@syu.ac.kr" class="auth_mail" title="E-mail the corresponding author ; wity_june@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Synthetic cathinones ; Conditioned place preference ; Self-administration ; Locomotor sensitization ; Abuse potential
- 刊名：Behavioural Brain Research
- 出版年：2017
- 出版时间：15 January 2017
- 年：2017
- 卷：317
- 期：Complete
- 页码：494-501
- 全文大小：1432 K
文摘
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We designed and synthesized a new synthetic cathinone BMAPN.
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BMAPN is a synthetic cathinone with naphthalene substituent on the aromatic ring.
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BMAPN produced rewarding and reinforcing effects.
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BMPAN has the ability to alter dopamine-related gene expression.