Rhodium(III)-catalyzed heteroatom-directed C-H allylation with allylic phosphonates and allylic carbonates at room temperature

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• 作者：Hyeim Jo ; Sangil Han ; Jihye Park ; Miji Choi ; Sang Hoon Han ; Taejoo Jeong ; Seok-Yong Lee ; Jong Hwan Kwak ; Young Hoon Jung ; In Su Kim ; ^{insukim@skku.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Allylation ; 2-Arylbenzothiazole ; Allylic phosphonate ; C&ndash ; H activation ; Catalytic
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：28 January 2016
• 年：2016
• 卷：72
• 期：4
• 页码：571-578
• 全文大小：734 K

文摘

The rhodium(III)-catalyzed mild and site-selective C–H allylation of 2-arylbenzo[d]thiazoles and 2-arylbenzo[d]oxazoles with allylic phosphonates and allylic carbonates is described. This transformation provides an efficient construction of C2-allylated, crotylated and prenylated 2-arylbenzo[d]thiazoles and 2-arylbenzo[d]oxazoles. In addition, this protocol can be applied to the formation of 2-arylbenzo[d]thiazole scaffolds containing an allylic alcohol group by using of 4-vinyl-1,3-dioxolan-2-one and vinyl oxirane as coupling partners.