The expression pattern and functional role of REIC/Dkk-3 in the development of cutaneous squamous cell carcinoma
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- 作者：Jung-Min Shina ; Dae-Kyoung Choia ; Hye-Young Kangb ; Kyung-Cheol Sohna ; Young Leea ; Chang Deok Kima ; Jeung-Hoon Leea ; Byung Cheol Parka ; b ; shinam73@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：REIC/Dkk-3 ; Squamous cell carcinoma ; Expression ; Inhibition
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：84
- 期：1
- 页码：88-96
- 全文大小：544 K
文摘
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REIC/Dkk-3 is involved in the early development of squamous cell carcinoma.
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REIC/Dkk-3 inhibited the formation of cutaneous squamous cell carcinoma in vivo test.
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The anti-cancer effect of REIC/Dkk-3 may arise from suppression of tumorigenic cancer cells and the regulation of cell cycle.