Composition of inflammatory cells regulating the response to concurrent chemoradiation therapy for HPV (+) tonsil cancer
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- 作者：Yoon Se Leea ; Ji Young Parkb ; Kyung Ja Chob ; Sung Bae Kimc ; Sang Wook Leed ; Seung-Ho Choia ; Jong-Lyel Roha ; Soon Yuhl Nama ; Sang Yoon Kima ; sykim2@amc.seoul.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tonsil cancer ; Human papillomavirus ; Inflammatory cells ; Tumor immunological microenvironment ; CD4 ; CD8 ; Tumor-associated macrophage
- 刊名：Oral Oncology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：51
- 期：12
- 页码：1113-1119
- 全文大小：1960 K
文摘
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HPV (+) tonsil squamous cell carcinoma (TSCC)-related death remain unresolved.
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CD4 (+), CD8 (+), and CD68 (+) cells were used to evaluate immunological condition.
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Peritumoral distribution and the numbers of these cells were related to prognosis.
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These differences could be determining factors for CCRT outcomes in HPV (+) TSCC patients.