CYP2C19 genotyping combined with on-clopidogrel platelet reactivity in predicting major adverse cardiovascular events in Chinese patients with percutaneous coronary intervention
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- 作者：Xiao-Fang Tangb ; 1 ; Ya-Ling Hanc ; 1 ; Jia-Hui Zhanga ; Jing Wanga ; Yi Yaoa ; Chen Hea ; Bo Xub ; Zhan Gaob ; Shu-Bin Qiaob ; Jue Chenb ; Yuan Wub ; Ji-Lin Chenb ; Run-Lin Gaob ; Yue-Jin Yangb ; dr_yuejinyang@126.com" class="auth_mail" title="E-mail the corresponding author ; Jin-Qing Yuanb ; dr_jinqingyuan@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Clopidogrel ; Genotyping ; CYP2C19 ; Platelet function test
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：147
- 期：Complete
- 页码：108-114
- 全文大小：458 K
文摘
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CYP2C19 genotyping or on-clopiodgrel platelet reactivity was an independent risk predictor of MACEs in Chinese patients.
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The aggregate positive results based on the two testing methods were a more powerful predictor of higher risk.
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The aggregate positive results showed independent and additive prognostic values for MACEs in patients undergoing PCI.