Paper-based solid-state electrochemiluminescence sensor using poly(sodium 4-styrenesulfonate) functionalized graphene/nafion composite film

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• 作者：Yuanhong Xu ; Baohua Lou ; Zhaozi Lv ; Zhixue Zhou ; Libing Zhang ; Erkang Wang ; ^{ekwang@ciac.jl.cn}
• 关键词：AFM ; Atomic force microscopy ; CC ; completely complementary sequence ; CE ; counter electrode ; CV ; cyclic voltammetry ; EC ; electrochemical ; ECL ; electrochemiluminescence ; EIS ; electrochemical impendence spectroscopy ; ¦¤Ep ; potential difference between the an
• 刊名：Analytica Chimica Acta
• 出版年：2013
• 出版时间：6 February, 2013
• 年：2013
• 卷：763
• 期：Complete
• 页码：20-27
• 全文大小：1173 K

文摘

Herein, highly efficient solid-state ECL sensor was introduced for the first time onto the screen printed electrodes of the paper-based chips (PCs) based on the composite film of poly(sodium 4-styrenesulfonate) functionalized graphene (PSSG) and Nafion. Attributed to the cooperative characteristics of both PSS and graphene, PSSG ensured both effective Ru(bpy)₃²⁺ immobilization and fast electron transfer of Ru(bpy)₃²⁺ in the composite film. The ECL behaviors at the developed sensor were investigated using tripropylamine as a representative analyte and low detection limit (S N^?1 = 3) of 5.0 nM was obtained. It also exhibited more excellent reproducibility (relative standard deviations of 0.63 % for continuous 45 cycles) and long-term stability (¡«80 % of its initial ECL intensity could be retained over 3 months). More importantly, assisted by the developed ECL sensor, discrimination of 1.0 nM single-nucleotide mismatch in human urine matrix could be realized on the PCs for the first attempt. Thus, the developed sensor was confirmed with the advantages of highly sensitivity, long-term stability, simplicity, low cost, disposability, high efficiency and potential applicability.