Activation effect of Ganoderma lucidum polysaccharides liposomes on murine peritoneal macrophages
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- 作者：Zhenguang Liu ; Jie Xing ; Yee Huang ; Ruonan Bo ; Sisi Zheng ; Li Luo ; Yale Niu ; Yan Zhang ; Yuanliang Hu ; Jiaguo Liu ; Yi Wu ; Deyun Wang ; dywang@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：GLPL ; Ganoderma lucidum polysaccharide liposome ; GLP ; Ganoderma lucidum polysaccharide ; PBS ; phosphate buffer solution ; FBS ; fetal bovine serum ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; PBS ; phosphate buffered saline ; EE ; entrapment efficiency ; DMSO ; dimethyl sulfoxide ; BL ; blank liposome ; NO ; nitric oxide ; iNOS ; nitric oxide synthase ; MHC II ; major histocompatibility complex class II molecule
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：82
- 期：Complete
- 页码：973-978
- 全文大小：1544 K
文摘
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GLPL significantly promote the NO production and iNOS activity of peritoneal macrophages.
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The phagocytic activity and expression of MHC II of peritoneal macrophages significantly increased by stimulation of GLPL.
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GLPL significantly stimulated macrophages to secrete IFN-γ, IL-1β and TNF-α.