Modulating luminescence of Tb3+ with biomolecules for sensing heparin and its contaminant OSCS
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- 作者：Yihui Hu ; Wenjing Guo ; Yubin Ding ; Hanjun Cheng ; Hui Wei ; 1 ; weihui@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Time-resolved luminescence ; Tb3+ ; Heparin ; Oversulfated chondroitin sulfate ; Luminescence probes
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：86
- 期：Complete
- 页码：858-863
- 全文大小：906 K
文摘
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A time-resolved luminescence biosensing system for heparin was developed.
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Sensitive and selective detection of heparin with the TRL sensing system was established.
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The sensing system was successfully used for monitoring heparin metabolism in living rats.
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A strategy to identify oversulfated chondroitin sulphate contaminant in heparin was developed.