In vitro effect of sodium arsenite on Echinococcus granulosus protoscoleces
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- 作者：Guoqiang Xinga ; Bo Wanga ; Ying Leib ; Chunli Liuc ; Zhuo Wanga ; Hongjuan Shib ; Rentan Yanga ; Wenjuan Qinb ; Yufeng Jiangb ; yufengjiang03@126.com" class="auth_mail" title="E-mail the corresponding author ; Hailong Lva ; lvhl1999@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Echinococcus granulosus ; Protoscoleces ; Sodium arsenite ; In vitro
- 刊名：Molecular & Biochemical Parasitology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：207
- 期：2
- 页码：49-55
- 全文大小：2270 K
文摘
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We incubated E. granulosus protoscoleces in vitro with NaAsO2 at different concentrations.
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NaAsO2 demonstrated dose- and time-dependent suppression against E. granulosus protoscoleces.
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NaAsO2 could induce ultrastructural damages of E. granulosus protoscoleces.
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Our results clearly demonstrated that NaAsO2 could enhance caspase-3 activity of E. granulosus protoscoleces.