S. aureus upregulated TGF-β1 and bFGF mRNA expression and secretion.
S.aureus increased the mRNA and protein expression of TLR2 and TLR4.
S. aureus increased the protein expression of p-NF-κB and p-c-jun.
The increase in TGF-β1 and bFGF expression was shown to be inhibited by AP-1- and NF-κB-specific inhibitors.