Prospective Pilot Study of Consolidation Chemotherapy With Docetaxel and Cisplatin After Concurrent Chemoradiotherapy for Advanced Head and Neck Cancer
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- 作者：Kyun Chan Lee ; Seok Ho Lee ; Yuna Lee ; Se Hoon Park ; Jinny Park ; Eun Kyung Cho ; Dong Bok Shin ; Jae Hoon Lee ; Dong Young Kim ; Seon Tae Kim
- 关键词：Head and neck cancer ; Consolidation chemotherapy ; Docetaxel ; Cisplatin
- 刊名：International Journal of Radiation Oncology*Biology*Physics
- 出版年：2008
- 出版时间：1 May 2008
- 年：2008
- 卷：71
- 期：1
- 页码：187-191
- 全文大小：116 K
文摘
Examination of the energetics of sound production usually requires measurement of species that will produce normal calls under unnatural circumstances. Such measurements are potentially compromised by stress-related changes in calling input (through a reduction in calling effort) or output (through forced use of sub-optimal singing burrows). To determine if such measurements are indeed affected by abstraction from a natural setting, we measured the energetics of song production in undisturbed mole crickets Gryllotalpa monanka and employed a new approach where the animal's singing chamber replaces the respirometry chamber normally used in studies of this type. It was therefore possible to measure metabolic rate (MR) of calling crickets in situ for animals within self-constructed burrows under natural conditions. Calling MR measured under these conditions averaged 13.5-fold higher than standard MR and 2.2-fold higher than MR measured during burrowing in the lab. The calling MR of G. monanka was similar to that measured for other calling insects, and to endothermic insects, but was only 10 % of that allometrically predicted for a similarly sized insect (0.89 g) during flight. A male mole cricket is estimated to consume 5.9 ml of oxygen during construction of a calling burrow and a 1-h calling bout; by comparison, a flying female would consume a similar volume in less than 6 min.