Heart rate–corrected QT interval duration is significantly associated with blood pressure in Chinese hypertensives

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• 作者：Shaojie Peng ; Yunxian Yu ; Ke Hao ; Houxun Xing ; Dong Li ; Changzhong Chen ; Aiqun Huang ; Xiumei Hong ; Yan Feng ; Yan Zhang ; Jianping Li ; Binyan Wang ; Di Wu ; Xiaobin Wang ; Xiping Xu
• 关键词：Essential hypertension ; QTc interval ; ECG ; Blood pressure ; Association ; Epidemiology
• 刊名：Journal of Electrocardiology
• 出版年：2006
• 出版时间：April 2006
• 年：2006
• 卷：39
• 期：2
• 页码：206-210
• 全文大小：158 K

文摘

Many studies demonstrated that a prolonged heart rate–corrected QT interval (QTc) increases the risk of malignant ventricular arrhythmias and sudden death.

Methods

We measured the electrocardiogram and blood pressure of 1480 hypertensive patients and assessed the relationship between the length of QTc and blood pressure.

Results

The mean QTc is longer in female than in male participants. There was a positive association between QTc and blood pressure in both men and women. The estimated increase in systolic and diastolic blood pressure for each 100-millisecond increase in QTc was 6.4 and 5.0 mm Hg in men and 3.7 and 2.5 mm Hg in women, respectively.

Conclusion

Our study demonstrated a significant positive relationship between the QTc interval and baseline blood pressure in a Chinese hypertensive population.