Characterization and antiviral activity of a newly identified defensin-like peptide, HEdefensin, in the hard tick Haemaphysalis longicornis

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• 作者：Melbourne Rio Talactac^a ; ^b ; ^e ; Yurika Yada^a ; Kentaro Yoshii^c ; Emmanuel Pacia Hernandez^a ; ^b ; Kodai Kusakisako^a ; ^b ; Hiroki Maeda^a ; ^b ; Remil Linggatong Galay^d ; Kozo Fujisaki^f ; Masami Mochizuki^a ; ^b ; Tetsuya Tanaka^a ; ^b ; ^{k6199431@kadai.jp}
• 关键词：HEdefensin ; Antimicrobial peptide ; Langat virus ; Haemaphysalis longicornis
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：68
• 期：Complete
• 页码：98-107
• 全文大小：2218 K
• 卷排序：68

文摘

The HEdefensin gene was identified from the hemolymph EST database of H. longicornis. The HEdefensin peptide has virucidal activity against LGTV in vitro. The HEdefensin gene may not be involved in antiviral immunity against LGTV in vivo.