Antiferritin VL homodimer binds human spleen ferritin with high specificity

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• 作者：Nymalm ; Yvonne ; Kravchuk ; Zinaida ; Salminen ; Tiina ; Chumanevich ; Alexander A. ; Dubnovitsky ; Anatoly P. ; et. al.
• 关键词：Antiferritin antibody ; VL domain ; Antibody light chain ; CDR loops ; X-ray structure ; Model structures
• 刊名：Journal of Structural Biology
• 出版年：2002
• 出版时间：June, 2002
• 年：2002
• 卷：138
• 期：3
• 页码：171-186
• 全文大小：822 K

文摘

The antiferritin variable light domain (VL) dimer binds human spleen ferritin (85 % L subunits) but with 50-fold lower affinity, K_a