Twenty healthy volunteers were investigated during 4 experimental steps: baseline, hyperoxia, ischemia, and reperfusion. For each volunteer, 2 sensors INVOS and 2 sensors EQUANOX were placed on both left and right calves. Blood pressure, heart rate, and peripheral pulse oximetry were monitored.
Peripheral rSO2 ranged from 40 % to 95 % (INVOS) and from 47 % to 100 % (EQUANOX): 81 ¡À 12 vs 82 ¡À 9 (P = .469). A significant relationship was found at baseline between absolute values of INVOS and EQUANOX (n = 40; R2 = 0.159; P = .011). Bias was ? 0.4 % , and limits of agreement were ¡À 15.1 % . The percent maximum differences vs baseline values during dynamic maneuvers were 33 % ¡À 19 % (95 % confidence interval, 24-42) and 21 % ¡À 14 % (95 % confidence interval, 15-28) for INVOS and EQUANOX, respectively. No significant relationship was observed between percent maximum differences in INVOS and EQUANOX (n = 20; R2 = 0.128; P = .122). Rates of desaturation/resaturation during occlusive vascular tests were 3.65 % per minute vs 2.36 % per minute (P = .027) and 30.42 % per minute vs 16.28 % per minute (P = .004) for INVOS and EQUANOX, respectively.
INVOS and EQUANOX are not comparable in measuring both absolute values and dynamic changes of peripheral rSO2 and near-infrared spectroscopy-derived parameters during occlusion vascular tests.