Intragastric hypertonic NaCl simulates osmotically active substances ingestion.
Intragastric hypertonic NaCl induces thirst, natriuresis and diuresis.
H2O2 in the brain may modulate behavioral and renal responses.
Central H2O2 decreased hypertonic NaCl-induced thirst and natriuresis.
Central H2O2 also decreased meal-associated water intake.