Decreased expression of long non-coding RNA WT1-AS promotes cell proliferation and invasion in gastric cancer
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- 作者：Tao Dua ; 1 ; sfgidt1982@163.com" class="auth_mail" title="E-mail the corresponding author ; Baogui Zhangb ; c ; 1 ; zyjzbg@126.com" class="auth_mail" title="E-mail the corresponding author ; Shun Zhanga ; v2zs@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Xiaohua Jianga ; jxh@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author ; Ping Zhenga ; zp1377@easthospital.cn" class="auth_mail" title="E-mail the corresponding author ; Jianfang Lic ; rjljf@163.com" class="auth_mail" title="E-mail the corresponding author ; Min Yanc ; ym10299@163.com" class="auth_mail" title="E-mail the corresponding author ; Zhenggang Zhuc ; zzg1954@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Bingya Liuc ; liubingya@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：lncRNAs ; long non-coding RNAs ; GC ; gastric cancer ; PRC2 ; Poly Repressive Complex 2 ; CCK-8 ; cell counting kit-8
- 刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1862
- 期：1
- 页码：12-19
- 全文大小：1684 K
文摘
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We identified WT1-AS as a new cancer related lncRNA WT1-AS in gastric cancer.
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WT1-AS regulated cell proliferation, cell cycle progression, migration and invasion.
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WT1-AS overexpression could decrease ERK protein phosphorylation.