Synthesis of novel amphiphilic hyaluronan containing-aromatic fatty acids for fabrication of polymeric micelles
详细信息 查看全文
- 作者：Alena Matelová ; a ; b ; Gloria Huerta-Angelesa ; huerta-angeles@contipro.com" class="auth_mail" title="E-mail the corresponding author ; Daniela &Scaron ; mejkalová ; a ; Zdislava Brůnová ; a ; Jan Du&scaron ; ekc ; Robert Ví ; chab ; Vladimí ; r Velebný ; a
- 关键词：Hyaluronan (CID 24728612) ; Resveratrol (CID 445154) ; Retinyl palmitate (CID 5280531) ; Benzoyl chloride (CID 7412) ; 4-Phenylbutanoic acid (CID 4775)
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 October 2016
- 年：2016
- 卷：151
- 期：Complete
- 页码：1175-1183
- 全文大小：1299 K
文摘
- •
ω-Phenylalkanoic acids were grafted to HA towards polymeric micelles fabrication.
- •
Benzoyl chloride was found as an economical activator of phenyl fatty acids.
- •
Hydrophobic compounds were successfully encapsulated in hydrophobized HA.
- •
Phenylalkyl fatty acids grafted-HA increased loading capacity due to π–π interactions.