Human HLA-Ev (147) Expression in Transgenic Animals
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- 作者：R. Matsuura ; matsuura@pedsurg.med.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; A. Maeda ; R. Sakai ; H. Eguchi ; P.-C. Lo ; H. Hasuwa ; M. Ikawa ; K. Nakahata ; M. Zenitani ; T. Yamamichi ; S. Umeda ; K. Deguchi ; H. Okuyama ; S. Miyagawa
- 刊名：Transplantation Proceedings
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：48
- 期：4
- 页码：1323-1325
- 全文大小：626 K
文摘
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A codon exchanged HLA-Ev (147) + IRES + human beta 2-microgloblin gene was established.
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The HLA-Ev on pig endothelial cell was confirmed to regulate natural killer cell− and macrophage-induced cytotoxicity.
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Mice with HLA-Ev (147) showed a relatively broad expression in each organ.