Dopamine receptor D2 and catechol-O-methyltransferase gene polymorphisms associated with anorexia nervosa in Chinese Han population: DRD2 and COMT gene polymorphisms were associated with AN
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- 作者：Sufang Penga ; Shunying Yua ; yushuny@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Qian Wangb ; Qing Kanga ; Yanxia Zhanga ; Ran Zhanga ; Wenhui Jianga ; Yiping Qiana ; Haiyin Zhanga ; Mingdao Zhanga ; Zeping Xiaoa ; Jue Chena ; chenjue2088@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anorexia nervosa ; Dopamine ; Gene polymorphism ; DRD2 ; COMT
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：11 March 2016
- 年：2016
- 卷：616
- 期：Complete
- 页码：147-151
- 全文大小：612 K
文摘
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Rs1800497 of DRD2 gene and rs4633 of COMT gene were associated with the susceptibility of AN within the Chinese Han sample.
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Allele C of rs1800497 was a protective factor.
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There was a gene–gene interaction between rs1800497 and rs4633.