Long non-coding RNA Unigene56159 promotes epithelial-mesenchymal transition by acting as a ceRNA of miR-140-5p in hepatocellular carcinoma cells
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- 作者：Jing Lv1 ; Hong-xia Fan1 ; Xiao-pei Zhao ; Ping Lv ; Jing-yi Fan ; Yi Zhang ; Min Liu ; Hua Tang ; htang2002@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Long non-coding RNA (lncRNA) ; HCC migration/invasion ; lncRNA-Unigene56159 ; Slug ; miR-140-5p
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 November 2016
- 年：2016
- 卷：382
- 期：2
- 页码：166-175
- 全文大小：3335 K
文摘
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Long non-coding RNA Unigene56159 expression is induced by HBV.
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Unigene56159 promotes cell migration/invasion and EMT in HCC.
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Unigene56159 functions as a ceRNA for miR-140-5p to de-repress the Slug expression.
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The Unigene56159/miR-140-5p/Slug axis contributes to HCC cell migration and invasion.