One-step construction of saturated six-membered rings directly using calcium carbide as an acetylene source: synthesis of 1,3,5-triaroylcyclohexanes

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• 作者：Zheng Li ; ^{lizheng@nwnu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Lili He ; Rugang Fu ; Geyang Song ; Wenli Song ; Demeng Xie ; Jingya Yang
• 关键词：Calcium carbide ; Saturated six-membered ring ; 1 ; 3 ; 5-Triaroylcyclohexane ; Renewable resources ; Sustainable chemistry
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：21 July 2016
• 年：2016
• 卷：72
• 期：29
• 页码：4321-4328
• 全文大小：1235 K

文摘

Saturated six-membered rings were constructed directly using calcium carbide as an acetylene source by one-step procedure, and functionalized cyclohexanes, 1,3,5-triaroylcyclohexanes, were efficiently synthesized by reactions of calcium carbide with aromatic or heteroaromatic aldehydes in high yield. This protocol has the advantages of using inexpensive and renewable resource, no flammable and explosive gas and no transition-metal catalysts.