Ketogenic diet attenuates spatial and item memory impairment in pentylenetetrazol-kindled rats
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- 作者：Yan Jiang1 ; Yuqiang Lu1 ; Mengmeng Jia ; Xiaohang Wang ; Zhengxiang Zhang ; Qun Hou ; drhouqun@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Baohui Wang ; wang.baohui888@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：KD ; ketogenic diet ; ND ; normal control diet ; PTZ ; pentylenetetrazol ; SE ; status epilepticus ; NOR ; novel object recognition ; NPR ; novel placement recognition ; MWM ; morris water maze
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：1646
- 期：Complete
- 页码：451-458
- 全文大小：1179 K
文摘
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KD decreased the body weight gain and the bregma-lambda length of rats.
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PTZ-induced kindling impaired the NOR and NPR exploratory ability in the ND group.
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KD attenuated the decrease of exploration ratio both in NOR and NPR in kindled rats.
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KD had a slight protective effect on spatial probe memory in MWM test.