Optimization of selenylation modification for garlic polysaccharide based on immune-enhancing activity
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- 作者：Zhenzhen Gaoa ; 1 ; Jin Chenb ; 1 ; Shulei Qiua ; Youying Lia ; Deyun Wanga ; Cui Liua ; Xiuping Lia ; Ranran Houa ; Chanjuan Yuea ; Jie Liua ; Hongquan Lic ; Yuanliang Hua ; ylhu@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：GPS ; garlic polysaccharide ; sGPSs ; selenizing garlic polysaccharide ; Se-P ; selenium polysaccharide ; NA-SS ; nitric acid-sodium selenite ; GA-SA ; glacial acetic acid-selenous acid ; GA-SS ; glacial acetic acid-sodium selenite ; SOC ; selenium oxychloride
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：136
- 期：Complete
- 页码：560-569
- 全文大小：1487 K
文摘
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Garlic polysaccharide (GPS) was modified in selenylation respectively by four methods.
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Contents and yields of selenium and immune-enhancing activities of sGPSs were compared.
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Selenylation modification can significantly enhance immune-enhancing activity of GPS.
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NA-SS method presented the highest selenylation efficiency and was the best method.
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sGPS5 displayed strongest activity and optimal modification conditions were gotten.