Syndecan-4, a PRRSV attachment factor, mediates PRRSV entry through its interaction with EGFR
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- 作者：Rui Wanga ; xybwr@126.com" class="auth_mail" title="E-mail the corresponding author ; Xin Wanga ; Bo Nia ; Chang-chao Huana ; Jia-qiang Wuc ; Li-bin Wend ; Ying Liaob ; Guang-zhi Tongb ; Chan Dingb ; Hong-jie Fana ; Xiang Maoa ; b ; xmao@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; xmao@shvri.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Porcine reproductive and respiratory syndrome virus ; Attachment ; Entry ; Syndecan-4 ; EGFR
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：24 June 2016
- 年：2016
- 卷：475
- 期：2
- 页码：230-237
- 全文大小：2199 K
文摘
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Syndecan-4 is a PRRSV attachment factor in MACR-145 cells.
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EGFR interacts with syndecan-4 in MACR-145 cells.
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SDC4-EGFR interaction is important for PRRSV entry in MARC-145 cells.