IL-10 regulate decidual Tregs apoptosis contributing to the abnormal pregnancy with Toxoplasma gondii infection
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- 作者：Kaixue Laoc ; 1 ; Mingdong Zhaob ; 1 ; Zhidan Lia ; 1 ; Xianbing Liua ; Haixia Zhanga ; Yuzhu Jianga ; Yanlin Wangc ; docylwang2003@126.com" class="auth_mail" title="E-mail the corresponding author ; Xuemei Hua ; xue-mei-hu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：IL-10 ; Regulatory T cells ; Apoptosis ; Abnormal pregnancy outcomes ; Toxoplasma gondii
- 刊名：Microbial Pathogenesis
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：89
- 期：Complete
- 页码：210-216
- 全文大小：1925 K
文摘
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Worse pregnancy outcomes were observed in infected IL-10−/− mice than infected mice.
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Cleaved Caspase-3 and Caspase-8 levels in Tregs increased with Toxoplasma gondii infection.
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IL-10 regulated Caspase-3 and Caspase-8 levels in Tregs with Toxoplasma gondii infection.