Gut-Colonizing Bacteria Promote C. elegans Innate Immunity by Producing Nitric Oxide
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- 作者：Yi Xiao1 ; 3 ; Fang Liu1 ; 3 ; Zhigang Zhang2 ; Jie Tang1 ; Cheng-Gang Zou1 ; chgzou@ynu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Ke-Qin Zhang1 ; kqzhang1@aliyun.com" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：16 February 2016
- 年：2016
- 卷：14
- 期：6
- 页码：1301-1307
- 全文大小：1938 K
文摘
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Bacterial diversity in C. elegans gut is distinct from that in soil
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B. subtilis is the most abundant bacterium in C. elegans gut
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B. subtilis produces nitric oxide to activate p38 MAPK in C. elegans
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p38 MAPK promotes C. elegans innate immunity against pathogens