Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China
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- 作者：Xinle Liu1 ; Bin Yang1 ; Lixin Li1 ; Bei Cai ; Yun Liao ; Linhui Li ; Zhiqiang Wu ; Lanlan Wang ; wanglanlan_lab@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ankylosing spondylitis ; HLA-DP/DQ ; STAT4 ; Gene polymorphism
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：10-15
- 全文大小：340 K
文摘
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HLA-DQ rs7453920 polymorphism was significantly related with the reduced risk of AS.
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No significant association was found between HLA-DP or STAT4 polymorphisms and AS.
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HLA haplotype block AAA and GGA significantly correlated with reduced risk of AS.
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Demonstrate the significant association of HLA-DQ and AS firstly in Southwest China.