Controllable targeted system based on pH-dependent thermo-responsive nanoparticles
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- 作者：Chengling Yang ; Hua Guo ; Zhenpeng Hu ; Zhiqing Tian ; Yukun Wu ; Wei Wang ; Zhi Yuan ; zhiy@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tumour targeting ; pH-dependent ; Thermo-responsive ; Reversible shielding
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2015
- 出版时间：1 November 2015
- 年：2015
- 卷：135
- 期：Complete
- 页码：802-810
- 全文大小：1910 K
文摘
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The pH-dependent thermo-responsive polymer was designed and prepared.
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The LCST of the well-designed polymer was pH-dependent.
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Surface properties and targeting ability of NPs could be switched within slight pH and temperature changes.
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The shielding/deshielding of targeting ligands was reversible.