New and improved tools and methods for enhanced biosynthesis of natural products in microorganisms

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• 作者：Zhiqing Wang ; Patrick C Cirino ^{pccirino@uh.edu}
• 刊名：Current Opinion in Biotechnology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：42
• 期：Complete
• 页码：159-168
• 全文大小：799 K
• 卷排序：42

文摘

Inducible gene suppression tools provide a powerful alternative to gene deletions. Implementing dynamic gene regulation balances fluxes and reduces metabolic toxicity. Custom transcription factors and riboswitches enable new strain evolution methods.