Distinct RNA transcriptome patterns are potentially associated with angiogenesis in Tie2-expressing monocytes
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- 作者：Xinjing Wang1 ; wxj2007@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Zhiyuan Dai1 ; dzypaper@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Xiaoli Wu smalllily2012@163.com" class="auth_mail" title="E-mail the corresponding author ; Kai Wang kaiwangcn@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Xipeng Wang ; Dr_xwang@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：TEMs ; Tie2-expressing monocytes ; miRNA ; microRNA ; lncRNA ; long non-coding RNA ; Tie2&minus ; ; monocytes ; monocytes that do not express Tie2 ; qRT-PCR ; quantitative real-time reverse transcription polymerase chain reaction ; GO ; Gene Ontology ; IGF1 ; insulin like growth factor 1 ; Ang2 ; angiopioetin2 ; TAMs ; tumor associated macrophages ; sncRNAs ; small non-coding RNAs ; PBMCs ; peripheral blood mononuclear cells ; FC ; fold change ; TFs ; transcription factors
- 刊名：Gene
- 出版年：2016
- 出版时间：10 April 2016
- 年：2016
- 卷：580
- 期：1
- 页码：1-7
- 全文大小：1061 K
文摘
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Transcriptome patterns of human TEMs were analyzed by microarray.
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Hundreds of RNAs including non coding RNAs were dysregulated in TEMs.
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Functional annotation of the dysregulated mRNAs by Gene Ontology
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Target genes of the dysregulated miRNAs were predicted.
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Cis/trans-regulation analysis of the dysregulated lncRNAs was performed.