Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer
详细信息 查看全文
- 作者：Mengying Zhang1 ; 2 ; 4 ; Hejun Liu1 ; 2 ; 4 ; 5 ; liuhejun@mail.ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yongxiang Gao1 ; 2 ; Zhongliang Zhu1 ; 2 ; Zijun Chen3 ; Peiyi Zheng1 ; 2 ; Lu Xue1 ; 2 ; Jixi Li3 ; Maikun Teng1 ; 2 ; mkteng@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Liwen Niu1 ; 2 ; lwniu@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hif1 ; H2A-H2B dimer ; histone chaperone ; nucleosome assembly ; SHNi-TPR ; NASP
- 刊名：Structure
- 出版年：2016
- 出版时间：4 October 2016
- 年：2016
- 卷：24
- 期：10
- 页码：1810-1820
- 全文大小：3510 K
文摘
- •
Crystal structure of Hif1 in complex with H2A-H2B
- •
Hif1 forms a specific chaperone-histone complex with H2A-H2B dimer
- •
Hif1 binds alternately to H2A-H2B and H3-H4 via distinct mechanisms
- •
Hif1 shares similar chaperone specificity to human sNASP