The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice
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- 作者：Xin Laia ; 1 ; Qingsheng Peib ; 1 ; Xu Songa ; 1 ; Xun Zhoua ; 1 ; Zhongqiong Yina ; yinzhongq@163.com" class="auth_mail" title="E-mail the corresponding author ; Renyong Jiaa ; c ; ; Yuanfeng Zoua ; Lixia Lia ; Guizhou Yued ; Xiaoxia Lianga ; Lizi Yina ; Cheng Lva ; Bo Jinga
- 关键词：Resveratrol ; Immunosuppressive mice ; Immune function ; NF-κB
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：33
- 期：Complete
- 页码：42-47
- 全文大小：1189 K
文摘
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This manuscript provides an assessment of resveratrol on reinforcing immunity recovery in immunosuppressive mice.
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Resveratrol could recover macrophage phagocytic function and promote the proliferation of splenic lymphocytes.
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Resveratrol could upregulate the percentage of CD4+ T cells and the expressions of cytokines related to the immunization.
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Resveratrol could activate NF-κB signaling to regulate series of immunological responses in a dose-dependent manner.