KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A
详细信息 查看全文
- 作者：Xiaojin Wu1 ; Yao Yao1 ; Xiaojing Bao1 ; 2 ; Huifeng Zhou1 ; Xiaowen Tang1 ; Yue Han1 ; Xiao Ma1 ; Yuejun Liu1 ; Jia Chen1 ; Haixia Zhou1 ; Song Jing1 ; Bing Gu1 ; Yang Xu1 ; Aining Sun1 ; Jun He1 ; 2 ; junhe1964@163.com" class="auth_mail" title="E-mail the corresponding author ; Depei Wu1 ; wudepei@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hematopoietic stem cell transplantation ; HLA-matched sibling donor ; KIR2DS4 ; KIR1D
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：22
- 期：2
- 页码：220-225
- 全文大小：814 K
文摘
- •
This study demonstrates that KIR2DS4 and its variant KIR1D are associated with outcomes for patients with a donors with KIR gene haplotype A in HSCT involving HLA-identical siblings.
- •
KIR2DS4/KIR1D subclassification is helpful for donor selection in recipients of sibling-related HLA-matched HSCT.