A novel ubiquitin-protein ligase E3 functions as a modulator of immune response against lipopolysaccharide in Pacific oyster, Crassostrea gigas
详细信息 查看全文
- 作者：Qi Cheng
- 关键词：Crassostrea gigas ; Ubiquitination ; Immune response ; Lipopolysaccharide stimulation ; Ub-protein ligase E3
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：60
- 期：Complete
- 页码：180-190
- 全文大小：2230 K
文摘
- •
- <p id="p0010">A ubiquitin-protein ligase E3 (CgE3Rv1) was identified from Crassostrea gigas.p>
- •
- <p id="p0015">The expression of CgE3Rv1 mRNA was highest in gonads and hemolymphs.p>
- •
- <p id="p0020">Its mRNA was up-regulated post LPS stimulation while decreased after ACh stimulation.p>
- •
- <p id="p0025">rCgE3Rv1-RINGv could induce the ubiquitination in vitro as a typical Ub-protein ligase E3.p>
- •
- <p id="p0030">CgE3Rv1 plays an important role in immune defense in C. gigas.p>