Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells
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- 作者：Xiaoting Jina ; Ruijun Sua ; Ruijin Lib ; Li Songa ; Meilan Chena ; Long Chengc ; Zhuoyu Lia ; d ; lzy@sxu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：PM2.5 ; Vitamin c ; Quercetin ; Mitochondria ; Inflammation ; 16HBE
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：144
- 期：Complete
- 页码：459-466
- 全文大小：1663 K
文摘
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Vitamin c and quercetin can relief the toxicity caused by PM2.5 on 16HBE cells.
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Vitamin c and quercetin prominently alleviate the PM2.5-induced ROS generation.
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Vitamin c and quercetin supplement significantly counteract the NOX2 and p67phox expressions incurred by PM2.5.
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Vitamin c and quercetin have suppressive roles in mitochondrial structure and function damaged by PM2.5.
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Vitamin c and quercetin play protective effects on inflammation response affected by PM2.5.