Toxic effects of zinc ions on kinesin - Potential molecular cause of impaired intracellular transport

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• 作者：Konrad J. Bö ; hm ^{kjboehm@gmx.de}
• 关键词：Zinc ions ; Kinesin ; Microtubules ; ATPase ; Motility
• 刊名：Toxicology Letters
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：268
• 期：Complete
• 页码：58-62
• 全文大小：1120 K
• 卷排序：268

文摘

Zinc ions are able to inhibit kinesin ATPase and kinesin-based motility generation. Zinc-induced inhibition depends on the zinc/magnesium ion ratio. Zinc-induced inhibition depends on temperature. Zinc-induced inhibition might be one molecular cause of impaired intracellular transport.