文摘
Sex-related differences were not reported for the atrial flutter (AF). The purpose of the study was to look for the influence of gender on indications, clinical data and long-term results of AFl ablation.
Methods
<p>985 patients, [227 females (23 % )] were referred for radiofrequency AFl ablation. Clinical history, echocardiography were collected. Patients were followed from 3 months to 10 years.Results
<p>Age of women and men was similar (65.5 ¡À 12 vs 64 ¡À 11.5 years). Underlying heart disease (HD) was as frequent in women as men (77.5 vs 77 % ), but women had more congenital HD (10 vs 2 % ;p < 0.001), valvular HD (18 vs 10 % ;p < 0.002), hypertensive HD (24 vs 18 % ;p < 0.05), and less chronic lung disease (5 vs 10 % ;p < 0.01), and ischemic HD (5 vs 20 % ;p < 0.001). Atrial fibrillation (AF) history was more frequent in women (36 vs 27 % ;p < 0.001). AFl-related tachycardiomyopathy (4.5 vs 8 % ;p < 0.03) was more frequent, but 1/1 AFl (10 vs 6 % ;p = NS) as frequent. Failure of ablation (16 vs 10 % ;p < 0.01), ablation-related major complications (3.5 vs 0.9 % ;p < 0.005) were more frequent in women. After 3 ¡À 3 years, AFl recurrences were as frequent in women and men (10 vs 14 % ), AF occurrence more frequent in women (34 vs 19.5 % ; p < 0.001). After excluding patients with previous AF, AF risk remained higher in women (19 vs 12 % ; p < 0.004).Conclusions
<p>In patients admitted for ablation, AFL was less common in women than in men, despite similar age and similarly prevalent HD. More than men, women had frequent AF history, a higher risk of failure of ablation and AFl ablation-related major complications and a higher risk of AF after ablation.
