Arnica montana effects on gene expression in a human macrophage cell line. Evaluation by quantitative Real-Time PCR
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- 作者：Debora Olioso
- 关键词：Arnica montana ; Macrophages ; Real-Time PCR ; Gene expression ; Wound healing ; Chemokines
- 刊名：Homeopathy
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：105
- 期：2
- 页码：131-147
- 全文大小：2491 K
文摘
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- <p id="p0010">Arnica montana is widely used to treat trauma, wounds and post-operative conditions but its action mechanisms are largely unknown.p>
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- <p id="p0015">Arnica dilutions 2c, 3c, 5c, 9c, 15c were tested on a human macrophage cell line looking at the expression of inflammatory genes.p>
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- <p id="p0020">Treatments caused slight but significant changes in the expression of several genes, often in a non-linear way with various dilutions.p>
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- <p id="p0025">In particular the gene CXCL1 exhibited a consistent increase of expression, suggesting a positive influence on cell recruitment and angiogenesis.p>