Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway
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- 作者：Li Zhanga ; b ; Xian Chengb ; Yanyan Gaob ; Chiyu Zhangc ; Jiandong Baob ; Haixia Guand ; Huixin Yub ; Rongrong Luc ; lurr@jiangnan.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Qiang Xua ; molpharm@163.com" class="auth_mail" title="E-mail the corresponding author ; Yang Suna ; yangsun@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Con A ; concanavalin A ; Curcumin ; Cur ; DMSO ; dimethyl sulfoxide ; DTCs ; differentiated thyroid carcinomas ; EMT ; epithelial&ndash ; mesenchymal transition ; LNM ; lymph node metastasis ; MET ; mesenchymal&ndash ; epithelial transition ; MMPs ; matrix metalloproteinases ; PTC ; papillary thyroid cancer ; TGF-β1 ; transforming growth factor β1 ; TIMPs ; tissue inhibitors of metalloproteinases.
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：341
- 期：2
- 页码：157-165
- 全文大小：3938 K
文摘
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Curcumin inhibits the adhesion, spreading and migration of BCPAP cells.
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Curcumin inhibits TGF-β1-induced EMT in BCPAP cells.
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Curcumin inhibits TGF-β/Smad2/3 signaling pathway in BCPAP cells.