Chitosan/poly(vinyl alcohol)/bovine bone powder biocomposites: A potential biomaterial for the treatment of atopic dermatitis-like skin lesions
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- 作者：Ná ; tali O. Alvesa ; Gabriela T. da Silvaa ; Douglas M. Weberb ; Cristiane Lucheseb ; Ethel A. Wilhelmb ; André ; R. Fajardoa ; andre.fajardo@pq.cnpq.br" class="auth_mail" title="E-mail the corresponding author ; drefajardo@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chitosan (PubChem CID ; 3086191) ; Poly(vinyl alcohol) (PubChem CID ; 11199) ; 2 ; 4-Dinitrochlorobenzene (PubChem CID ; 6) ; Sodium tripolyphosphate (PubChem CID ; 24455) ; Acetic acid (PubChem CID ; 176) ; Hydrochloric acid (PubChem CID ; 313) ; Serum albumin (PubChem CID ; 16132389) ; Calcium chloride (PubChem CID ; 5284359) ; Sodium chloride (PubChem CID ; 5234)
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：5 September 2016
- 年：2016
- 卷：148
- 期：Complete
- 页码：115-124
- 全文大小：2187 K
文摘
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Chitosan, poly(vinyl alcohol) and bovine bone powder biocomposites were designed.
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The biocomposites have reliable physicochemical properties to be used as biomaterials.
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The biocomposites were assessed to treat DNCB-induced skin lesions in an AD-like model.
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In vivo assays show that the biocomposites can attenuate and treat AD skin lesions.