Comparison of Cobas® HPV and Anyplex™ II HPV28 assays for detecting and genotyping human papillomavirus

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• 作者：Christophe Pasquier^a ; ^b ; ^c ; ^{pasquier.c@chu-toulouse.fr} ; Karine Sauné ; ^a ; ^b ; ^c ; Sté ; phanie Raymond^a ; ^b ; ^c ; Jé ; rô ; me Boisneau^c ; Monique Courtade^b ; ^c ; ^d ; Jacques Izopet^a ; ^b ; ^c
• 关键词：Human papillomavirus ; Real-time PCR ; HPV genotyping ; Anyplex&trade ; II HPV28
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：87
• 期：1
• 页码：25-27
• 全文大小：222 K
• 卷排序：87

文摘

Persistent infection with high-risk human papillomavirus (HPV-HR) is a recognized cause of cervical cancer. The aim of this study was to compare analytical and clinical performances of the Cobas® HPV and Anyplex™ II HPV28 assays for HPV detection and genotyping. A total of 94 cervical samples were tested. For HPV-HR, the results agreed very well (94.68%), with 100% agreement when detecting CIN2+. The Anyplex™ II HPV28 assay detected more genotypes than the Cobas® HPV Test, but their clinical performances were similar.