CD44 enhances macrophage phagocytosis and plays a protective role in Streptococcus equi subsp. zooepidemicus infection

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• 作者：Qiang Fu^a ; ^b ; Zigong Wei^b ; Pingping Xiao^b ; Yaosheng Chen^b ; Xiaohong Liu^b ; ^{liuxh8@mail.sysu.edu.cn}
• 关键词：CD44 ; Macrophages ; Phagocytosis ; Streptococcus equi subsp. zooepidemicus
• 刊名：Veterinary Microbiology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：198
• 期：Complete
• 页码：121-126
• 全文大小：1654 K
• 卷排序：198

文摘

CD44 promotes the recruitment of macrophages to infect lungs. CD44 deficiency impairs the binding of S. zooepidemicus to macrophage. CD44 deficiency increased bacterial outgrowth and dissemination.