Daidzein increases OPG/RANKL ratio and suppresses IL-6 in MG-63 osteoblast cells
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- 作者：Jing Suna ; b ; 1 ; Wei Jia Sunc ; 1 ; Zheng Yang Lid ; 1 ; Ling Lib ; Yue Wanga ; e ; wangyue6808@126.com" class="auth_mail" title="E-mail the corresponding author ; Yu Zhaoe ; Cong Wange ; Li Ren Yua ; Ling Zhi Lia ; f ; Yong Liang Zhanga ; g ; zhang78127@tom.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Daidzein ; OPG ; RANKL ; IL-6 ; ERE
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：32-40
- 全文大小：1831 K
文摘
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Daidzein increases OPG/RANKL expression ratio in MG-63 cells.
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Daidzein suppresses IL-6 expression in MG-63 cells.
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Daidzein increases OPG/RANKL ratio, suppresses IL-6 production through the ER pathway.
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The effects of daidzein on OPG/RANKL expression are mediated by both ERα and ERβ.
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The effects of daidzein on IL-6 production primarily by ERα