Interaction between hippocampal serotonin and cannabinoid systems in reactivity to spatial and object novelty detection
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- 作者：Mohammad Nasehia ; Nasehi@iricss.org" class="auth_mail" title="E-mail the corresponding author ; Elnaz Rostam-Nezhadb ; Mohaddeseh Ebrahimi-Ghiric ; Mohammad-Reza Zarrindastd ; e ; f ; g ; h ; zarinmr@ams.ac.ir" class="auth_mail" title="E-mail the corresponding author
- 关键词：CB1 receptors ; 5-HT4 Receptors ; Spatial and object novelty detection memory ; Mice
- 刊名：Behavioural Brain Research
- 出版年：2017
- 出版时间：15 January 2017
- 年：2017
- 卷：317
- 期：Complete
- 页码：272-278
- 全文大小：671 K
文摘
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Activation or blockade of 5-HT4 receptors impaired spatial memory.
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CB1 receptors activation impaired spatial and novelty, while their blockade facilitated novelty.
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Subthreshold dose of RS67333 restored ACPA response.
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Subthreshold dose of RS23597 differently affect ACPA signaling.
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Effective dose of AM251 blocked the effect of 5-HT4 agents on ACPA responses.