Light-induced retinal damage using different light sources, protocols and rat strains reveals LED phototoxicity
详细信息 查看全文
- 作者：A. Krigel ; M. Berdugo ; E. Picard ; R. Levy-Boukris ; I. Jaadane ; L. Jonet ; M. Dernigoghossian ; C. Andrieu-Soler ; A. Torriglia ; alicia.torriglia@inserm.fr" class="auth_mail" title="E-mail the corresponding author ; F. Behar-Cohen ; francine.behar@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AMD ; age-related macular degeneration ; BRB ; blood retinal barrier ; CCFL ; Cold Cathode fluorescent lamps ; CFL ; fluorocompact lamp ; ERG ; electroretinogram ; LE ; Long Evans ; LED ; Light Emitting Diode ; ONL ; outer nuclear layer ; PBS ; phosphate-buffered saline ; PNA ; peanut agglutinin ; W ; Wistar
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：17 December 2016
- 年：2016
- 卷：339
- 期：Complete
- 页码：296-307
- 全文大小：2505 K
文摘
- •
White LEDs induce stronger retinal degeneration than fluorocompact lamps.
- •
Pigmentation induces very little protection in LED-exposed rats at high luminance.
- •
Exposure to LED induces breakdown of the external blood-retinal barrier.