Tat PTD-Endostatin-RGD: A novel protein with anti-angiogenesis effect in retina via eye drops
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- 作者：Yan Lia ; Lian Lia ; Zhiwei Lib ; Juzheng Shenga ; Xinke Zhangc ; Danyang Fenga ; Xu Zhanga ; Fengxin Yina ; Aijun Wangc ; Fengshan Wanga ; d ; fswang@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Neovascularization ; Oxygen-induced retinopathy ; Corneal barriers ; Blood-retina barrier
- 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：1860
- 期：10
- 页码：2137-2147
- 全文大小：2053 K
文摘
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Tat PTD-Es-RGD could inhibit angiogenesis in vitro.
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Tat PTD-Es-RGD could penetrate corneal and BRB model in vitro.
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Tat PTD-Es-RGD had high binding affinity to integrin αvβ3.
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Tat PTD-Es-RGD performed high activity for OIR treatment via eye drops.